Traditional viral vaccine production uses a trans-bottle culture process with adherent cells. This technique has the disadvantages of being limited by cell growth and cell density, low viral yield, high costs, and intensive labor. With the advancement of modern biotechnology and technical innovation from leading vaccine manufacturers, the drift towards applications involving suspension cell culture technologies for viral vaccine production has become an inevitable trend. JSBio has independent intellectual property rights of the suspension cell culture process development platform we use, which can provide overall solutions for vaccine manufacturers. These services pave the way for technological innovation in the industry, enterprise transformation, and upgrading.

• Extensive project experience

• Serum-free, chenmically defined media with independent intellectual property rights to shorten the domestication time and achieve one-step serum removal

• Application to a variety of cell lines

• A variety of mammalian cell lines have been successfully adapted to suspension cell growth using our technology

• Matching serum-free media and chemically defined media

• Disposable RotaTek Bioreactor Process scale up service

JSBio offers a suspension cell process development platform where we will adapt the client’s adherent cells to suspension growth and provide cell line development services for these cells.

• Cell banking (standard formulation or custom formulation)

• Adherent cell adaption to suspension growth (standard formulation or custom formulation)

• Process development using a shaker platform, monitoring cell

• Growth and virus production (Cell and viral growth media and process optimization)

• Small scale process, 2 L Bioreactor

• Pilot scale process, 50 - 200 L Bioreactor

Adherent cell lines(such as MRC-5, Vero etc.) can be used for vaccine production. JSBio can provide the following micro-carrier adherence cell platform services：

• Matching low or serum free media

• Micro-carrier process and scale up services

Cell Culture Media for Vaccine     Media Formulation Development    Custom Media Manufacturing